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Newsflash

Neuropsychiatric Inventory (NPI)

Setting the Standard for Alzheimer Research

What is the Neuropsychiatric Inventory (NPI)?

npi_test_set

The NPI has served as an outcome measure in many pharmacologic and nonpharmacologic intervention studies.

Measuring behavior in your trial may provide critically important outcome data useful in understanding and explaining the value of treatment. The NPI is the behavior instrument most widely used in clinical trials of antidementia agents.

The NPI uses a screening strategy to minimize administration time, examining and scoring only those behavioral domains with positive responses to screening questions. Both the frequency and the severity of each behavior are determined. Information for the NPI is obtained from a caregiver familiar with the patient's behavior.

More About the NPI


Why use the NPI Test?

Why use the NPI?

  • Established reliability and validity
  • Available in multiple languages
  • Can test many neurologic disorders
  • Most trial sites are familiar with the NPI
  • Ability to provide investigator training
  • Integrated caregiver distress measure
  • The Food and Drug Administration (FDA) is familiar with the NPI
  • NPI symptoms can be used in trials to determine the effect of treatment

More NPI Uses in Clinical Trials

 


All NPI case report forms must carry the copyright notification (© JL Cummings, 1994; permission for commercial use required; npiTEST.net.) The NPI or portions thereof may not be republished without the permission of the originator:  any republication must carry the copyright notification (© JL Cummings, 1994; permission for commercial use required; npiTEST.net.)

Complete rules for use of the NPI

 

Pharmaceutical Companies

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